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In a 4-year CV outcomes trial (Trial 7), 4,825 patients were randomized to semaglutide tablets for a median follow-up of 49.6 months and 4,825 patients were randomized to placebo for a median follow-up of 49.4 months [see Clinical Studies (14.4)]

The treatment areas

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Months 12+: Long-Term Results Average weight loss: 14-15% by month 16-17 (28-30 pounds for a 200-pound person) In the STEP-1 trial, participants reached their maximum weight loss around week 60-68 (months 14-16)

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These peptides work through complementary mechanisms, and many users report enhanced results when using them together